O, yorgun olduğu gerçeğine rağmen çalışmaya devam etti.
- In spite of the fact that he was tired, he continued working.
Onun meşgul olduğu gerçeğine rağmen, o beni görmeye geldi.
- In spite of the fact that she was busy, she came to see me.
... lt's a little-known fact that although horses first evolved in the Americas, ...
... And having built the index and dealt with the fact that ...