O, yorgun olduğu gerçeğine rağmen çalışmaya devam etti.
- In spite of the fact that he was tired, he continued working.
Tom çok parası olması gerçeğine rağmen iyi bir adam.
- Tom is a nice guy in spite of the fact that he has a lot of money.
... And having built the index and dealt with the fact that ...
... bright. And the fact that you're making an investment in higher education is critical. ...