osteogenesis

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The formation and development of bone
{i} formation of bone
The formation or growth of bone
osteogenesis imperfecta
a hereditary disease characterized by brittle bones that easily fracture
Osteogenesis Imperfecta
{i} hereditary disorder in which bones fracture and break easily from little or no obvious cause
osteogenesis imperfecta
autosomal dominant disorder of connective tissue characterized by brittle bones that fracture easily
osteogenesis imperfecta
Group of connective-tissue diseases in which the bones are very fragile. Several forms probably reflect different degrees of expression of the same disorder. Persons with osteogenesis imperfecta type I are normal at birth, but fractures occur easily; in van der Hoeve syndrome the sclerae are bluish, bone deformities in the skull cause deafness, double-jointedness occurs, and skin is abnormally thin. Babies with osteogenesis imperfecta type II, if not stillborn, are born with fractures, and fractures continue to occur, causing severe crippling; survival to adulthood is rare