monoklonal

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Turkish - English
monoclonal
genetically engineered from a single clone; used especially of a protein or antibody
forming or derived from a single clone
Myeloma develops from a single malignant plasma cell (monoclone) The type of Myeloma protein produced is also monoclonal, i e a single form rather than many forms (polyclonal) The important practical aspect of a monoclonal protein is that it shows up as a sharp spike (M spike) in the serum protein electropheresis test
The cells that are derived from a single common ancestor cell are part of a single clone For example, all leukemias, lymphomas, and myeloma are the result of the malignant transformation of a single cell and are monoclonal diseases If those cells are immunoglobulin-producing cells (B lymphocytes or their derivative plasma cells), the immunoglobulin protein they make is of one restricted type, referred to as monoclonal protein The group of neoplastic diseases that form monoclonal proteins are referred to as monoclonal gammopathies
In immunochemistry (the field of chemistry concerned with chemical studies of antigens and antibodies) pertaining to a protein from a single clone of cells
Myeloma develops from a single malignant plasma cell (monoclone) The type of myeloma protein produced is also monoclonal; a single form rather than many forms (polyclonal) The important practical aspect of a monoclonal protein is that it shows up as a sharp spike (M spike) in the serum electrophoresis test
having or being derived from a single clone
Pertaining to a protein from a single clone of cells, all molecules of which are the same; e g , in the case of Bence Jones protein, the chains are all kappa or lambda
something produced from a single clone, especially a monoclonal antibody
Derived from a single clone
Population of cells that was derived by cell division from a single ancestral cell
A group of cells that consist of a single clone, i e , all cells are derived from the same single ancestral cell