(hastalık) iyileştirilmesi zor

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refractory
Difficult to treat

In 33 adult patients with long standing refractory epilepsy on treatment with one or two standard anti-convulsant drugs,.

not amenable to control
not responding to treatment; "a stubborn infection"; "a refractory case of acne"
Resistant to decomposition
1) Heat-resistant material, usually non-metallic, used for furnace linings etc , 2) the quality of resisting heat
a heat-resistant material
difficult to melt or work; resistant to heat
Not responding to treatment
Elements that are refractory have a high vaporization temperature Conversely, these will be the first elements to solidify in a cooling environment
– Resistant to treatment
Refractory people are difficult to deal with or control, for example because they are unwilling to obey orders. refractory priests who refused to side with the king. = recalcitrant. adj. Material that is not deformed or damaged by high temperatures, used to make crucibles, incinerators, insulation, and furnaces, particularly metallurgical furnaces. Refractories are produced in several forms: molded bricks of various shapes, bulk granular materials, plastic mixtures consisting of moistened aggregates that are rammed into place, castables composed of dry aggregates and a binder that can be mixed with water and poured like concrete, and mortars and cements for laying brickwork
Non-metallic materials suitable for use at high temperatures; usually composed of aluminas, silicas, etc
resistant to authority or control; "as refractory as a mule"
material, such as brick, that has a very high melting point
not responding to treatment; "a stubborn infection"; "a refractory case of acne
{s} stubborn, obstinate; resistant to usual treatments; difficult to fuse or process
A condition that is resistant to ordinary treatment
A ceramic material used in high-temperature structures and equipment; potentially vulnerable to damage when used in ultra-high-power transformers in steel plants (Source: Mintzer, 1992)
A refractory person
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