mutation

(Tıp, İlaç) Çerçeve kayması mutasyonu (frameshift): bir genin protein kodlayan kısmında ya da birkaç baz çiftinin girmesi ya da çıkması ile oluşan mutasyon çeşididir

system mutation

sistem mutasyon

undergo reversion, as in a mutation

Gibi bir mutasyon içinde eski haline dönme tabi

acquired mutation

(Pisikoloji, Ruhbilim) edinilmiş mutasyon

chemical mutation

(Kimya) kimyasal değişiklik

chromosome mutation

(Botanik, Bitkibilim) kromozom mütasyonu

lethal mutation

(Biyoloji) letal mütasyon

pointer mutation

(Tıp) noktavi mutasyon

English - English

Definition of mutation in English English dictionary: Any heritable change of the base-pair sequence of genetic material; a mutant; any alteration or change; the act or process of change; A change in a gene that can occur randomly (naturally) or that can be deliberately caused in the laboratory by scientists; a change or alteration in form or qualities; (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism; Gradual definitely tending variation, such as may be observed in a group of organisms in the fossils of successive geological levels; Change; alteration, either in form or qualities; A permanent structural alteration in DNA that can be transmitted from one generation to the next Changes in DNA either have no effect or cause harm Occassionally a mutation can improve an organism's chance of surviving and passing the beneficial change on to its descendants; Change in the structure of a gene or chromosome; Change of the hereditary information resulting in a change in the sequence of the nucleotides in the DNA; A term introduced in the late-nineteenth century to refer to large scale phenotypic change but which was appropriated by modern genetics to mean any genetic change, large or small A 'point mutation' is the single substitution of one base A 'translocation' is the reshuffling of a long sequence An 'inversion' is the inverting of a long sequence, and so on; an alteration or change; Any inheritable change in DNA sequence; Any heritable change in the base-pair sequence of genetic material, namely DNA (or RNA in the case of some viruses); A permanent structural alteration in DNA In most cases, DNA changes either have no effect or cause harm, but occasionally a mutation can improve an organism's chance of surviving and passing the beneficial change on to its descendants 1; The occurrence of mutations, and the hereditary transmission, under some conditions, of the characters so appearing, are well-established facts; whether the process has played an important part in the evolution of the existing species and other groups of organisms is a disputed question; Alteration in the genetic material of a cell that is transmitted to the cell's offspring. Mutations may be spontaneous or induced by outside factors (mutagens). They take place in the genes, occurring when one base is substituted for another in the sequence of bases that determines the genetic code, or when one or more bases are inserted or deleted from a gene. Many mutations are harmless, often masked by the presence of a dominant normal gene (see dominance). Some have serious consequences; for example, a particular mutation inherited from both parents results in sickle-cell anemia. Only mutations that occur in the sex cells (eggs or sperm) can be transmitted to the individual's offspring. Alterations caused by these mutations are usually harmful. In the rare instances in which a mutation produces a beneficial change, the percentage of organisms with this gene will tend to increase until the mutated gene becomes the norm in the population. In this way, beneficial mutations serve as the raw material of evolution; n (myoo-TAY-shun) Change in a gene or chromosome resulting in a new trait or characteristic that can be inherited Mutation can be a source of beneficial genetic variation, or it can be neutral or harmful in effect; Any nucleotide change in DNA sequence; An error in replication or other alteration of the nucleotide base sequence creating a change in the sequence of base pairs on a DNA molecule If the change occurs in the DNA of a somatic cell, the mutation may cause a change in the organism's phenotype (leading, for example, to cancer) but will not affect the organism's offspring; only mutations in the germ cells can cause heritable changes in the offspring; a change in the genetic material within a living cell; A heritable change in DNA sequence at the level of the gene, the chromosome, or the genome; A truncation or change in the normal order of molecules in DNA that defines a specific gene A disease-causing mutation in a gene alters the gene blueprint and thus ultimately disrupts the construction of the normal protein encoded by the gene; a change in the number, arrangement, or molecular sequence of a gene; {i} act of mutating; change, alteration; state of having inheritable traits that differ from those of the parent; umlaut (Phonetics); Any heritable change in DNA sequence See also: polymorphism Return to Top; A genetic term A mutation is a change in the genetic code from what is considered normal Mutations can occur normally and not all mutations are harmful; The result of the above process; a suddenly produced variation; A change in the genetic information; a change or alteration in form or qualities (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism; - A sudden change in the string of DNA that makes up a gene in an organism; As now employed (first by de Vries), a sudden variation (the offspring differing from its parents in some well-marked character or characters) as distinguished from a gradual variation in which the new characters become fully developed only in the course of many generations; (biology) an organism that has characteristics resulting from chromosomal alteration; This term usually refers to a change in the sequence of the gene which codes for a protein If the sequence of the DNA gene is changed in any way, it will usually cause a change in the sequence in amino acids making up the protein that the gene codes for This can be a problem if the mutation is not intentional because it essentially means you are working with the wrong protein However, sometimes we make a mutation in a gene on purpose, such as the one we made to add on the histidines on the end of CFTR We did this by changing (mutating) the sequence of the CFTR gene carried by the baculovirus; a change in the character of a gene that is perpetuated when a cell divides or a virus replicates; Any heritable change in genetic material This may be a chemical transformation of an individual gene (a gene or point mutation), which alters its function On the other hand, this change may involve a rearrangement, or a gain or loss of part of a chromosome, which may be microscopically visible This is designated a chromosomal mutation Most mutations are harmful; a change in a gene; A mutation is a change in the parent DNA sequence or genetic code caused by exposure to chemicals and radiation; A change (in the number, arrangement, or molecular sequence ) in the sequence of DNA coding in a gene that occurs by chance, or due to some external influence A permanent, heritable change in a gene or chromosome structure; A change in the genetic material of a cell
aspirate mutation: A type of pronunciation change required when speaking certain Celtic languages
frameshift mutation: a genetic mutation that either inserts or deletes a series of nucleotides that is not divisible by three and thus disrupts gene expression by codons
hard mutation: A type of pronunciation change required when speaking certain Celtic languages
missense mutation: A point mutation that results in the substitution of one amino acid by another
mixed mutation: A type of pronunciation change required when speaking certain Celtic languages
mutationally: In a mutational manner
mutationally: With regard to mutation
nasal mutation: A type of pronunciation change required when speaking certain Celtic languages
nonsense mutation: A point mutation that generates either a premature stop codon, or a codon that does not specify any amino acid
point mutation: A mutation that involves the replacement, addition or deletion of a small number of bases (especially just one) at a specific site within a gene
soft mutation: A type of pronunciation change required when speaking certain Celtic languages
amber mutation: (Tıp, İlaç) (genetics) Alteration of a codon to UAG, one of the three codons that result in premature polypeptide chain termination in all living organism
back mutation: A reversal process whereby a gene that has undergone mutation returns to its previous state
mutationally: through mutation, in a manner characterized by genetic change
mutations: are the changes of a gene from one allelic form to another (i e , the nucleotide sequence changes)
mutations: plural of mutation
mutations: Permanent changes in the genetic material (DNA)
mutations: changes in the DNA that codes for a gene, which may or may not cause a normal working gene to become a non-working gene
mutations: rare changes in the DNA of genes which eventually lead to genetic diversity
point mutation: a mutation due to an intramolecular reorganization of a gene
point mutation: A mutation that changes only one small area or one nucleotide in a gene