One type of white blood cell Monocytes (macrophages) play a key role in phagocytosis The also interact with lymphocytes to regulate the immune response
A type of white cell that represents about five to ten percent of the cells in normal human blood The monocyte, along with the neutrophil, are the two major microbe-eating and killing cells in the blood When monocytes leave the blood and enter the tissue they are converted to macrophages The macrophage is the monocyte in action and can combat infection in the tissues, can ingest dead cells (scavenger), and can assist lymphocytes in their immune functions
Large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles
White cells that represent about 5% of circulating blood cells They are responsible for processing foreign materials (antigens), & the destroying cells & tissue debris that are by products of inflammation Normal range = 0 2-1 0
3-8% of leukocytes - Manufactured in the marrow, these cells become macrophages (phagocytes) when they leave circulation and mature in the tissues (See neutrophils, above, for discussion of phagocytosis ) Differentiation to macrophages is promoted by colony-stimulating factor Once a macrophage performs its "fair share" of phagocytosis, it dies, however, it may live in the tissues for years