heterozygosity

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(Tıp) Bakınız: Heterozygosis
English - English
雜合性,異型結合性, The presence of different alleles at one or more loci on homologous chromosomes
The condition of having one or more pairs of dissimilar alleles
The presence of different alleles at one or more loci on homologous chromosomes
The state of being heterozygous
refers to having different alleles (forms) of a particular gene
The condition of being heterozygous
genetic variability among individuals within populations and variability among populations
The percentage of people in a population who are heterozygous for a particular gene or marker; a measure of genetic diversity
The presence of different alleles at one or more loci on homologous chromosomes Source : Human Genome Project Information
{i} (Biology) state of being heterozygous, state of containing a dissimilar pair of genes for any hereditary characteristic
in an individual, two different alleles at one locus
the state of being heterozygous; having two different alleles of the same gene
The presence of different alleles on homologous chromosomes
loss of heterozygosity
DNA loss that occurs early in tumor development The extent of loss can range from a few million nucleotide pairs to an entire chromosome Specific cancers tend to lose certain chromosomal regions, resulting in characteristic patterns of LOH
loss of heterozygosity
A genetic event that can occur in the dividing cells of a diploid organism heterozygous for one or more markers, in which a daughter cell becomes homozygous or hemizygous for one or more alleles through mitotic recombination, deletion, or gene conversion "Loss of heterozygosity (LOH)" events are often important steps in tumor progression See the animation of this concept by Robert J Huskey at the Univeristy of Virginia
loss of heterozygosity
Describes a locus (or loci) at which a deletion or other process has converted the locus from heterozygosity to homozygosity or hemizygosity Phenomenon can lead to cancers by loss of tumor suppressor genes