listen to the pronunciation of prothrombin
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A glycoprotein, produced in the liver, that is converted into thrombin during bleeding and subsequent clotting
Carbohydrate-protein compound in plasma essential to coagulation. In response to bleeding, a complex series of clotting-factor interactions leads to its conversion by thromboplastin to thrombin, which transforms fibrinogen in plasma into fibrin. Fibrin and platelets combine to form a clot. Hemophilia is caused by a hereditary lack of one of the clotting factors. Vitamin K is needed to synthesize prothrombin, so conditions that impair the vitamin's absorption result in prothrombin deficiency and a tendency to prolonged bleeding
a protein in blood plasma that is the inactive precursor of thrombin
{i} blood protein involved in the clotting process