O, yorgun olduğu gerçeğine rağmen çalışmaya devam etti.
- In spite of the fact that he was tired, he continued working.
Tom çok parası olması gerçeğine rağmen iyi bir adam.
- Tom is a nice guy in spite of the fact that he has a lot of money.
... spite of the fact that the question came into the light, ...
... And a year ago at Moscone we celebrated the fact that we ...