a form of neuropathy that can begin between childhood and young adulthood; characterized by weakness and atrophy of the muscles of the hands and lower legs; progression is slow and individuals affected can have a normal life span; inheritance is X-linkedrecessive or X-linked dominant
born Nov. 29, 1825, Paris, Fr. died Aug. 16, 1893, Morvan French medical teacher and clinician. With Guillaume Duchenne (b. 1806 d. 1875) he is considered the founder of modern neurology. In 1882 he opened Europe's greatest neurological clinic of the day. An extraordinary teacher, he was known for his work with hysteria and hypnosis, which influenced many students, including Sigmund Freud. He described the symptoms of locomotor ataxia and the disintegration of ligaments and joint surfaces it causes (Charcot disease, Charcot joint), pioneered the linking of brain sites with specific functions, and discovered miliary aneurysms in the brain