O, yorgun olduğu gerçeğine rağmen çalışmaya devam etti.
- In spite of the fact that he was tired, he continued working.
38 yaşında olması gerçeğine rağmen, o hâlâ ebeveynlerine bağımlı.
- In spite of the fact that he's 38, he's still dependent on his parents.
... spite of the fact that the question came into the light, ...
... lt's a little-known fact that although horses first evolved in the Americas, ...