prion

listen to the pronunciation of prion
İngilizce - Türkçe
(Tıp) prion
İngilizce - İngilizce
A petrel from the genus Pachyptila
The etiologic agent of transmissible spongiform encephalopathies. The only self-replicating cause of disease known to lack nucleic acids
A self-propagating alternative conformer of any protein
a very small piece of protein that is thought to cause some brain diseases such as BSE (proteinaceous (19-21 centuries) + infectious particle). Disease-causing agent, discovered by Stanley Prusiner, responsible for various fatal neurodegenerative diseases called transmissible spongiform encephalopathies. An abnormal form of a normally harmless protein found in mammals and birds, the disease-causing prion can enter the brain through infection, or it can arise from a mutation in the gene that encodes the protein. Once present in the brain it causes normal proteins to refold into the abnormal shape. As prion proteins multiply, they accumulate within nerve cells, destroying them and eventually causing brain tissue to become riddled with holes. Diseases caused by prions include Creutzfeldt-Jakob disease, mad cow disease, and scrapie. Prions are unlike all other known disease-causing organisms in that they appear to lack nucleic acid (DNA or RNA)
(microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system
{i} theoretical infectious agent that is composed only of a protein (and has no genetic material)

İlgili Terimler

prion protein
A protein found on the surface of many mammalian cell types, especially neurons. The normal function of the prion protein is not known
prions
plural of prion
Türkçe - İngilizce
(Tıp) prion