the development of a particular disease, including the specific events involved, bodily tissues or systems affected, mechanisms of damage and timing of the course of disease
The origin and development of disease More specifically, it's the way a microbe (bacteria, virus, etc ) causes disease in its host
Why intraocular pressure of any degree leads to optic nerve damage is unknown Studies have shown that distrubances in axoplanic flow occur with elevated pressure Others implicate the microvasculature of the optic nerve head--specifically the posterior ciliary arteries and their role in microinfarction of the nerve head