الإنجليزية - الإنجليزية
تعريف orthologue في الإنجليزية الإنجليزية القاموس.
- one of two or more homologous gene sequences found in different species
- either of two or more homologous gene sequences found in different species
- - Orthologs are equivalent genes in different species that evolved from a common ancestor by speciation
- Groups of genes or proteins from different organisms that have the same function, are said to be orthologous There are numerous genes that have been conserved through evolutionary history The protein products can be identified in yeast, a nematode worm and human cells, for example It can be interesting to study the gene function in a worm, if you know that it has the same function in humans
- a sequence in another species that shares a direct common ancestor with the current sequence For some time after a speciation event this relationship is easily inferred and cleanly defined since the two genes differ only modestly As evolutionary time passes, the orthology relationship becomes less obvious and eventually becomes ill-defined because of duplication and divergence In the evolutionary limit, all sequences are probably derived from a single common ancestor (thought to be RNA)