apoptosis

listen to the pronunciation of apoptosis
İngilizce - Türkçe
(Tıp, İlaç) Apoptozis veya Apoptoz, (Yunanca: apoptosis yani "(ayrılarak) düşmek", apo="-den/-dan" ve ptosis="düşmek") programlanmış hücre ölümünün ana tiplerinden biridir. Bu tıp vücutta ihtiyaç duyulmayan veya anormalleşmiş hücrelerden kurtulmanın normal yoludur. Akut hücresel zarar sonucu olan hücre ölümü tipi nekrozdan farklı olarak apoptoz belirli bir moleküler işlemler serisinin (sırasının) sonunda hücrenin ölümünü sağlar ve aynı zamanda organizmanın yaşam döngüsü için gerekli ve yararlıdır. Örneğin gelişen bir embriyoda insan parmaklarının farklılaşması parmaklar arasındaki hücrelerin apoptoz başlatması gerekir ki parmaklar birbirinden ayrılabilsin
(Biyoloji) Bir organizmanın hücrelerinin normal olarak ölümü
apoptoz
apoptozis
İngilizce - İngilizce
A process of programmed cell death by which cells undergo an ordered sequence of events which lead to death of the cell, as occurs during growth and development of the organism, as a part of normal cell aging, or as a response to cellular injury

Cells may undergo apoptosis if they have sustained unrepairable damage.

or programmed cell death Mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. It may be initiated when a cell is no longer needed, when a cell becomes a threat to the organism's health, or for other reasons. The aberrant inhibition or initiation of apoptosis contributes to many disease processes, including cancer. Though embryologists had long been familiar with the process of programmed cell death, not until 1972 was the mechanism's broader significance recognized. Apoptosis is distinguished from necrosis, a form of cell death that results from injury
(Tıp, İlaç) (Physiology) the death of cells which occurs as a normal part of an organism's development
Disintegration of cells into membrane-bound particles that are then eliminated by phagocytosis or by shedding
Programmed cell death that plays an important role in both development and cancer induction
The process of natural cell death that eliminates injured or genetically damaged cells
Programmed cell death
Programmed cell death, that is, the death of cells by a specific sequence of events triggered in the course of normal development (e g , cells between digits in the limb bud) or as a means of preserving normal function (e g , in response to viral infection)
Process of cell death that results from turning on specific, active processes in the cell that lead the cell to kill itself This happens normally in some tissues, for example, during embryonic development when some groups of cells are removed from the animal In these apoptotic cells during development, genes are turned on as part of the developmental process that cause the cell to kill itself In other non-developmental cases of apoptosis, factors from outside the cell can cause the target cell to turn on apoptosis leading to its own death A way for a lay-person to view apoptosis is as a form of cell suicide
Normal cellular process involving a genetically programmed series of events leading to the death of a cell
a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival
{i} programmed cell death, natural process in which a cell disintegrates after reaching a certain age or due to poor cell health
Apoptosis is controlled cell death initiated by various signals indicating that the cell is in a status beyond repair
Programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells See also: cell
A process of "programmed cell death" by which cells undergo an ordered sequence of events which lead to death of the cell, as occurs during growth and development of the organism, as a part of normal cell aging, or as a response to cellular injury
A normal cellular process involving a genetically programmed series of events leading to the death of a cell
is the fragmentation of cells into tiny particles that are then engulfed by phagocytes or immune cells
The death of a cell as programmed by the genes that occurs when a cell ages or when an individual's health condition dictates Cancer cells avoid this natural cell behavior
Programmed cell death If apoptosis is affected, the cell well not die, causing a malignant or cancerous condition
death of a cell which is programmed by a set of specific genes Apoptosis of chondrocytes allows osteoblasts to attach to their calcified matrix, and the epithelial cells forming webs between the fingers to die
A genetically determined process of intracellular cell destruction postulated to exist and to be activated by a stimulus or by the removal of a suppressing agent or stimulus in order to explain the orderly breakdown and elimination of superfluous or unwanted cells (called also programmed cell death)
(ay' pu toh sis) - A series of genetically programmed events leading to cell death
Apoptosis signifies a process in which certain signals lead cells to self-destruct This is one way by which the organism protects itself against cells which have taken the first step in the transformation into cancer cells Cancer cells, on the other hand, often carry mutations that make them resistant to this form of cell death
process of cell death not associated with phlogosis Generally, this process is physiological, and involves nitric oxide The excessive presence of NO, due to the i-NOS activation, is able to excessively induce this process, provoking damage such as the onset of vasculopathy
Fragmentation of a cell into membrane-bound particles that are then eliminated by phagocytosis Programmed cell death
gene-directed cell death or programmed cell death that occurs when age, condition, or state of cell health dictates Cells that die by apoptosis do not usually elicit the inflammatory responses that are associated with necrosis Cancer cells are not able to undergo apoptosis
Programmed cell death In certain situations, cells can use molecules such as p53 to commit suicide
Programmed cell death; a physiologic process conserved to remove unwanted cells
Programmed cell death, that is, the death of cells by a specific sequence of events triggered in the course of normal development (e g cells between digits in the limb bud) or as a means of preserving normal function (e g in response to viral infection)
apoptosis

    Telaffuz

    Etimoloji

    () Coined in 1972 by John F. Kerr et al. in their article "Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics" published in volume 26 of the British Journal of Cancer. Derived from the Ancient Greek term ἀπόπτωσις (“a falling off”), from the roots ἀπό (“away from”) and πτωσις (“falling”)