To render unquiet; to deprive of peace, rest, or tranquility; to make uneasy or restless; to disturb
Disquiet is a feeling of worry or anxiety. There is growing public disquiet about the cost of such policing. = uneasiness
If something disquiets you, it makes you feel anxious. This information disquieted him. + disquieting dis·qui·et·ing He found her letter disquieting. anxiety or unhappiness about something disquiet over/about/at