1918

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influenza epidemic of 1918-19
or Spanish influenza epidemic Most severe influenza outbreak of the 20th century. It apparently started as a fairly mild strain in a U.S. army camp in early March 1918. Troops sent to fight in World War I spread the virus to western Europe. Outbreaks occurred in nearly every inhabited part of the world, spreading from ports to cities along transportation routes. Pneumonia often developed quickly and killed within two days. Among the most deadly epidemics in history, it left an estimated 25 million dead; unusually, half the deaths were among 20-to 40-year-olds