subplate

Englisch - Englisch

Definition von subplate im Englisch Englisch wörterbuch

(Tıp, İlaç) Subplate neurons are among the first generated neurons in the mammalian cerebral cortex (Kostovic & Rakic, 1980). These neurons disappear during postnatal development and are important in establishing the correct wiring (McConnell et al. 1989, Ghosh & Shatz, 1992) and functional maturation (Kanold et al. 2003) of the cerebral cortex. Subplate neurons appear to be selectively sensitive to injury (such as hypoxia) which in humans are associated with motor and cognitive defects (McQuillen & Ferriero 2005)